Welcome to the Michigan Integrative Musculoskeletal Health Core Center
The Michigan Integrative Musculoskeletal Health Core Center (MiMHC) is supported by a P30 grant from NIH/NIAMS. This award is a great honor and reflects the hard work and dedication of all musculoskeletal (MSK) researchers at U of M. There are over 100 faculty members of the MiMHC. These investigators plus their research teams together make Michigan a highly productive and collaborative environment to conduct MSK research!
The theme of the MiMHC is understanding mechanisms of musculoskeletal health, injury, and disease across the lifespan.
The goal of this center is to strengthen existing and develop new musculoskeletal programs by providing the following support:
- discounts for routine procedures
- access to specialized equipment and technical expertise
- scientific advice on experimental design and data acquisition, analysis and interpretation
- opportunities to expand and engage the MSK community in collaborative research
- mentorship of Trainees and Junior Faculty
- promotion of greater interactions among basic scientists and clinicians
- promotion of research focusing on interactions across MSK tissues, across time, and between sexes
The Resource Cores centralize specialized technologies and expertise across all physiological length scales, enabling center investigators to conduct “vertically” oriented science from molecular mechanisms to organ- and organismal-level function. The MiMHC supports three Resource Cores:
- Histological Assessment Core – plastic and paraffin embedding, access to specialized equipment for sectioning and staining
- Structural and Compositional Assessment Core – micro/nanoComputed Tomography, Raman spectroscopy
- Functional Assessment Core – physiological testing, microsurgery support, muscle mechanics, tendon testing, bone testing, custom fabrication/machining
The Enrichment Program will promote and sustain new interactions among center investigators, enabling the interdisciplinary team to conduct “horizontally” oriented science to identify mechanisms of injury and disease arising as a result of interactions between musculoskeletal tissues or with other physiological systems. The Enrichment Program focuses on community building, junior faculty mentorship, and grantsmanship. The Enrichment Program also offers pilot grant opportunities aimed at promoting greater interactions among clinicians and basic scientists and supporting research projects studying interactions across musculoskeletal tissues, across time, and between sexes. Please see the Enrichment Program page for more information on applying for Pilot grants; proposals for the 2020 Enrichment Program grant year are now being accepted.
The Third Annual Musculoskeletal Health Symposium was held Monday, April 29, 2019. This year's keynote speaker was Charlotte A. Peterson, Ph.D., who presented "Evolving roles for satellite cells in skeletal muscle adaptation and aging". The full agenda can be found here.