May 19, 2021

9:00am - 4:00pm

Virtual "Zoom" meeting

External Advisors:

Karyn Esser, PhD

Louis C. Gerstenfeld, PhD

Clifford J. Rosen, MD

Keynote Speaker:

Deneen Wellik, PhD

The 5th Annual Musculoskeletal Health Symposium was held on Wednesday, May 19, 2021 via "Zoom"; in addition to Dr Wellik's keynote presentation the symposium featured a poster session highlighting work by junior faculty, trainees, students, fellows, staff, and house officers. Trainees (students, fellows, house officers) were eligible to compete for 1 of 3 travel awards ($750/award). Awardees were selected as follows: abstracts designated for the poster competition were judged and 6 finalists were selected to give short podium presentations at the Symposium. Of these, 3 were selected for travel awards announced at the end of the meeting.

Agenda (Eastern Times): The full agenda is available here . Also available for download is the Poster Abstract book. Links to here the presentations will be available soon.

900-915 Welcome and Update on the MiMHC - Karl J. Jepsen, PhD

915-1045 Travel Award Competition (Renny Franceschi, PhD Moderator)

Sudipta Baroi, “PPARG in osteocytes controls sclerostin expression, bone mass, marrow adiposity and mediates TZD-induced bone loss”

Melanie Beaulieu, PhD “The ACL can hypertrophy in response to mechanical loading: An MRI study in elite athletes”

Shawn Hallett, “Chondrocytes in the resting zone of the growth plate are maintained in a Wnt-inhibitory environment”

Jacqueline LaRouche, “Natural killer cell and neutrophil imbalances prevent muscle stem cell mediated regeneration”

Hsiao Hsin Sung, “Effects of sclerostin antibody on the peri-implant osseointegration in an osteogenesis imperfecta mouse model”

Emilie Henning, “Multiple metrics indicate that deep learning-based bone segmentation of CT data outperforms other methods”

1045-1100 Break

1100-1200 Keynote Address (Karl Jepsen, PhD Moderator)

Deneen Wellik, PhD “Hox gene regulation of adult skeletal homeostasis and repair”

1200-100 Poster Session – website: https://mimhc-2021symposium.virtualpostersession.org/

100-200 Lunch Break

200-315 2018/9 Pilot Grant Awardees (Susan Brooks, PhD Moderator)

Gregory Clines, MD PhD “Osteoblasts generate androgens that feed prostate cancer growth: A new mechanism of bone metastasis”

Alexis Donneys, MD “Delivery of Jagged-1 to enhance non-vascularized bone grafting in the irradiated mandible”

Ormond MacDougald, PhD “Roles for bone marrow adipocytes in the functioning of bone and hematopoietic cellularity”

Daniel Michele, PhD “Visualizing membrane repair in contraction-induced injury”

Megan Weivoda, PhD “Functional and affinity-based targeting of biotherapeutics to sites of active bone remodeling”

315-330 Award Presentation & Conclusion - Renny Franceschi, PhD