Eighth Annual Musculoskeletal Health Symposium

Modified histological image of muscle wasting associated with cancer cachexia. Adapted from https://ludwigcancer.princeton.edu/research/research-areas/cachexia

May 16, 2024

9:00am - 4:15pm

D. Dan and Betty Kahn Auditorium and Atrium

A. Alfred Taubman Biomedical Science Research Building

External Advisors:

Karyn Esser, PhD

Louis C. Gerstenfeld, PhD

Clifford J. Rosen, MD

Keynote Speaker

Teresa Zimmers, PhD

Professor of Cell, Developmental and Cancer Biology 

School of Medicine

Oregon Health & Science University



The 8th Annual Musculoskeletal Health Symposium will be held on Thursday, May 16, 2024 in the Biomedical Science Research Building, BSRB; in addition to the keynote presentation the symposium will feature a poster session highlighting work by junior faculty, trainees, students, fellows, staff, and house officers. Trainees (students, fellows, house officers) are eligible to compete for 1 of 3 travel awards ($650/award). Awardees will be selected as follows: abstracts designated for the poster competition will be judged and 6 finalists selected to give short podium presentations at the Symposium. Of these, 3 will be selected for travel awards to be announced at the end of the meeting.


We are very excited about the opportunity for our community coming together for this event to celebrate the incredible MSK research being conducted at UM and our collaborative institutions. Thank you to all (inside or outside UofM) who are able to attend.


We would appreciate you forwarding an invitation to others (inside or outside UM) that may be interested in attending. Here is a downloadable flyer on the Symposium you can share with others.


Please use the following link to register: https://www.eventbrite.com/e/annual-2024-musculoskeletal-health-symposium-tickets-866589942847. Upon registration you will be provided a Zoom link if you plan to attend virtually. There is no cost to register. Any questions regarding registration, please contact Sarah Boston (sjayers@med.umich.edu).

Agenda:  The full agenda is available as a pdf file download and printing.

830 Refreshments (BSRB Rooms A/B/C)

900-915 Welcome and MiMHC Update – Megan Killian, PhD

915-1045 Travel Award Competition (Renny Franceschi, PhD Moderator)

Boya Zhang“Affinity-targeting of anti-sclerostin antibody to the bone surface significantly increases therapeutic efficacy in an ovariectomy mouse model of osteoporosis”

Carlos Urrego“Development of a mouse model to evaluate changes in female bone architecture, mechanics, and osteocyte senescence with type 2 diabetes”

Easton Farrell - “Piezo1 overaction induces a myofibroblast phenotype in synovial fibroblasts via YAP1”

Leeann Flowers - “AMPK signaling is dysregulated in tendinopathy, and loss of AMPKα1 leads to age-associated cell, matrix, and mechanical dysfunction in mouse achilles tendon”

Rafael Correia Cavalcante - “New genetic mouse models for temporomandibular joint homeostasis with mechano-environment”

Stephanie Steltzer - “Development of engineered tendon tissue micro-gauges(tenTuGs) for investigating tendon organization and mechanobiology”

1045-1100 Break

1100-1200 Poster Session (BSRB Lobby)

1200-130 Lunch - provided (BSRB Rooms A/B/C)

130-230 Keynote Address (Karl Jepsen, PhD, Moderator)

Teresa Zimmers, PhD - “Mechanisms of muscle loss in physiological and pathological cachexia” 

230-410 MiMHC Faculty Presentations (Susan Brooks, PhD Moderator) 

Aimee Colbath, VMD, PhD / Abigail Loucks, PhD (P&F awardee) - “Identifying the role of mast cells in post-traumatic osteoarthritis”

Andrew Ludlow, PhD (P&F awardee) - “Discovery of the impact of exercise on skeletal muscle mRNA isoform expression

Claire Kalpakjian, PhD

Todd Bredbenner, PhD - “Defining “normal” in a heterogeneous population”

Eileen Crawford, MD - “How do healthcare disparities impact the musculoskeletal care journey in the young, athletic population?” 

410-415 Award Presentations & Conclusion - Renny Franceschi, PhD

Image: Modified histological image of muscle wasting associated with cancer cachexia. Adapted from https://ludwigcancer.princeton.edu/research/research-areas/cachexia